Rather than just depending on anti-histamine drugs to treat allergy symptoms, in my opinion the better strategy is to find out what you are allergic to and take steps to avoid, filter or eliminate your contact with the allergens. I only use anti-histamine as a last resort, preferring to breathe through an N95 mask, scarf or my T-shirt when I encounter allergens in public -- and vigilantly remove allergens in my home.
"Histamine is best known as a mediator of allergic reactions, but it is now recognized to participate in numerous other normal and pathologic processes."
What Does Histamine Do?
The Functions of Histamine
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